Phone:1.508.421.4800
1.877.421.4801 (Toll Free)
Fax :1.508.421.4801
Email:info@biocytogen.com
- Animal models
- Customer Animal Model services
- Tag antibodies
- Internal control antibodies
- Pathological antibodies
- Cell/Tissue DNA Extraction
Kit(Spin-column) - Gel DNA purification kit
- Endo-free Plasmid DNA maxi-prep kit
- High-purity Plasmid DNA Mini-preparation Kit(Spin-column)
- Endo-free Plasmid Mini-preparation Kit(Spin-column)
- Plasmid DNA Maxi-preparation Kit(Spin-column)
Antibody
Molecular Biology Products
In vivo:
ILŠ\17A is actively expressed in some intraepithelial lymphocytes (IELs) of small intestine. Isolated small intestine IELs were stained directly without stimulations. Fig 1 shows the GFP expression in IELs of ILŠ\17AŠ\GFP mice.
TGFbeta and ILŠ\6 effects on GFP expression: Sorted na.ve CD4+ T cells were stimulated with plate bound antiŠ\CD3/antiŠ\CD28 in the absence or presence of TGFb (1ng/ml) and ILŠ\6 (20ng/ml). GFP expression was
analyzed after 48 hours of stimulation (Figure 2) .
Our company designs and develops novel and extremely sensitive cytokine reporter mice used for high-through-put screening (HTS) of small pharmaceutical compounds for autoimmune disease treatments.
Our company also supports worldwide life science research by providing carefully designed gene targeting mouse models. Biocytogen provides ultra-clean Specific Pathogen Free (SPF) mice to non-profit academic research entities and for-profit pharmaceutical entities, eliminating the need for quarantine and re-derivation. Instead of using 129 genetic background ES cells, all mouse models generated are in C57BL/6 genetic background, which saves years-of-time compared to backcross breeding. Utilizing our mouse models will save both time and money.